Maria Abe is one of only three known vampires in the world and he desires nothing more than to be helpful to humans. Maria grew up as a clumsy and shy child who was scared of accidentally hurting humans with his powers. Tokuko Nanami met Maria when they were just children and has made it her duty to watch over and protect Maria almost like a third parent. Although Tokuko has always been the one protecting him, Maria wished to be able to protect her and make her see him as something more. The manga follows their daily lives as high school students and watches as they become closer than just friends.

Fushigi no Maria-kun is a lighthearted comedy manga with a sprinkle of romance that is similar to the less serious scenes of Sennen no Yuki. Both manga feature a vampire who dislikes the idea of drinking the blood of humans due to not wanting to burden them. Although both manga go about it in different ways, both Maria and Touya grow throughout their stories, as they come to face their problems with being a vampire in human society. Tokuko and Chiyuki play similar roles in the development of their vampire counterparts, with Tokuko and Chiyuki proving that not all humans are bad and will not discriminate against vampires.

After growing tired of the formal ways of the demon world, Vivi decided to leave the demon world and live on Earth. One day when he arrived at home, Vivi discovered a child on his porch and decided it would be fun to raise the child. 14 years later, the child, now named Hana, has grown to enjoy her life with the demon Vivi and his butler Toni. Hana is quite fond of Vivi and often brings him flowers despite them wilting when Vivi touches them and she wishes to be by his side for as long as she can. Vivi has also grown attached to Hana, he wishes to take care of Hana no matter what, even going as far as to not let her touch him for fear that she might wilt like the flowers.

Hana to Akuma and Sennen no Yuki both feature the romances that involve a human girl and supernatural beings. The supernatural main characters in both Hana to Akuma and Sennen no Yuki struggle with their interactions with their human counterparts and aren't able to accept their feelings so easily due to the fear of ultimately losing them. Both manga have more serious tones, focusing on the main human member of the relationships eventual death and the fear of losing each other. Despite the darker tone, both manga have nice romance stories that can easily melt the heart of the reader as it can make them cry.

Kana Takachiho is an outgoing girl who was great at sports until an accident stops her from being able to play sports and causes her to lose her scholarship. Kana got hit by a car when she jumped into a crosswalk while chasing Aki, a boy she recognized from her childhood. After she was hit, Kana learns that Aki is a vampire as he uses his power to heal her and turning her into his immortal servant. Despite Aki's cold demeanor, he promises to protect Kana from the evil forces that are trying to stop Aki. Aki's goal is to find the seven “Stigmas” so he can wake up his twin brother who has fallen into a mysterious coma.

The main similarity between Junketsu + Kareshi and Sennen no Yuki are its strong heroines. Kana and Chiyuki are both outgoing and friendly towards everybody despite the tragedies that they have gone through in their lives. These incidents cause them to become the strong characters they are at the beginning of their respective manga. Both series also incorporate many supernatural characters and elements outside of the single vampire that is introduced from the start. Junketsu + Kareshi is different from many of the manga on this list with is action and fighting scenes, but it still has the romantic and comedic banter that is featured in all of the manga on this list

A recent string of peculiar crimes involving young girls that appear to have been attacked by a vampire has put the people of the city on edge. Catholic school student Hinata Sorazono has begun to suspect her new neighbor, Junya Tokinaga, of being the culprit. Junya is the author of a popular romance novel involving vampire and human relationships and is seen leaving home at all hours of the night. Hinata decides to follow Junya out one night to see if he is really a vampire, but before she is able to discover anything, Hinata gets attacked by a man with a knife. Before she gets hurt, Junya jumps in to save her from the attacker. Hinata and Junya start to spend more time together after the incident, the more Hinata learns about Junya the more she questions if he is a human or a vampire.

Mitsu-aji Blood and Sennen no Yuki both tell the stories of supernatural beings who struggle with their lives as vampires. In both manga, the vampires sucking blood is shown to mean more complicated than the vampires just getting a meal. The emotions and bigger meaning behind the vampires sucking blood drive both stories and serve as the major plot point tying everything together. Mitsu-aji Blood and Sennen no Yuki both focus on the relationships between their main characters and spend a majority of their time developing these relationships while sprinkling in a little comedy.

While on her way to take her entrance exams, Hiyo Osora stopped to help a crow which caused her to fail her entrance exams. Luckily, she received an acceptance letter from a school she had never heard of called SM Academy. After she learned her father had recommended her to the school, Hiyo gladly accepts and decides to attend SM Academy. When she arrives, Hiyo meets the head of the student council, Kurou Tenma, and he escorts her to the welcoming ceremony. There Hiyo learns that not only is Kurou her fiance, but everyone attending the school is actually a monster. Now, stuck at the school for a year, Hiyo must get used to her new life surrounded by these mysterious monster people and learn more about the man she is arranged to marry.

Sennen no Yuki and Love Monster feature stories about girls that encounter supernatural characters and start to develop relationships with them. You will find romance, drama, and a lot of comedy in both series, but they also feature many series plot points that deal with facing one's mortality and learning to trust others after a life filled with people hating you. While Love Monster is much more risque than Sennen no Yuki, both manga focus primarily on the relationship between the budding romantic relationship between its main characters. Sennen no Yuki and Love Monster both expertly develop their characters, with Toya and Kurou shown to be struggling with their lives as supernatural monsters while Chiyuki and Hiyo go through struggles of their own and grow to be able to stand on their own.

Kiyo Katsuragi is a school girl who just inherited her grandmother's mansion. When she arrives at the mansion, Kiyo is surprised to see that she isn't alone. There are two half-vampires, Kuroboshi and Alshu living in the mansion already. Things get even more complicated when Kurobushi decides he wants to take Kiyo as his bride and in turn, become his only source of blood. Kiyo declines the offer and their relationship gets off to a rough start. Kiyo must learn to coexist with the vampires living in her mansion while also trying to maintain her normal everyday life.

Bloody Kiss and Sennen no Yuki have many similarities when it comes to their romantic comedy. Both manga feature a young girl who meets a vampire that she gets involved with. Neither Kiyo nor Chiyuki is surprised by the fact that vampires exist and they end up befriending the vampire. A romantic rival is introduced in both series that knows of the vampire's existence and think they would be better for the heroine despite them not being normal themselves. Outside of the romantic comedy, both serious also feature some more serious plot lines that make their stories stand out despite both of the stories only being a few chapters long.