Hataraku Saibou!! (Cells At Work!! Season 2) – Your Favourite Bio Class Keeps Getting Better!

Our favourite biology class is back with a second season (as well as a spin-off) and we’re absolutely delighted with how it’s turning out so far! After the hilarious, interesting, and dramatic first season, Hataraku Saibou!! (Cells At Work!!) brings us another closeup of day-to-day life inside the human body! What does the second season of Cells At Work have in store for us, especially after that intense rollercoaster of a finale in season 1? Here’s what we found out!

Platelet Mommy

One really welcome addition to Cells At Work is the introduction of the cell that produces the cute little rascals responsible for clotting blood. The Megakaryocyte is the proverbial mother of the Platelets and in Cells At Work, she is characterized as a rough and tough master who teaches the blood platelets everything they know! The first episode of Season 2 gives us ample kawaii factor with the episode being focused on a special little Platelet, Backwards Cap, who runs into White Blood Cell while trying to train her body to become more useful to her fellow Platelets.

The first episode is incredibly cute and the important humorous element of Cells At Work is highlighted by the personification of the Platelet Mommy, Megakaryocyte. The best part of her introduction is how she bribes the Platelets into an inspired performance to manage the effects of a bump to the head, using positive reinforcement and a gold medal to spur the adorable little ones into action!


T-Memory Cells are important immunocytes that retain records of the immune system’s past battles and throughout the first season of Cells At Work, T-Memory Cell has been a recurring character. In the second episode of Season 2, T-Memory Cell sees a vision of colossal destruction caused by a strange virus. Memory seems to have no recollection of the body’s previous encounter with the enemy and thinks it to be a vision of the future. When the virus makes an appearance soon after, Memory’s panic is sent into overdrive as he saw immense death and destruction. However, after being hit on the head by B-Cell, Memory realizes that he was seeing memories of the body’s vaccination against Mumps, which in turn allows them to dispatch the virus with a cannon created specifically for that effort. The remaining leucocytes are disappointed to find the action all over, and Memory is embarrassed and teased for thinking of his memories as a prophetic vision.

A More Episodic Workplace

Hataraku Saibou!! (Cells At Work!!) is a well-thought out parody of the inner workings of the human body. Its commitment to the personification of human cells and a reimagination of how the human body works means that there isn’t a set storyline nor is one necessary. To that end, as from the second episode of the second season, Cells At Work!! adopts a more episodic approach to the series, with there being multiple parts to each episode instead of one storyline followed in an episode. This appears to be more in-tune with the gag element that is the foundation of Cells At Work!! and a step in the right direction for the series.

Final Thoughts

Cells At Work!! is a brilliant comedy that brings together a stunning visual appeal with a creative and insightful approach to its content. Each episode is uniquely entertaining and even educational, with interesting explanations to various bodily phenomena given a packaging anime fans are quite familiar with – the third episode of Season 2 brought us a hilariously blatant Jojo’s Bizarre Adventure Easter Egg that just upped the experience. Seeing the nexus between anime, anime culture, and education regarding the human body work out this well only serves to strengthen the notion that anime can make anything more interesting than it already is!

Hataraku-Saibou-Wallpaper-4-700x396 Hataraku Saibou!! (Cells At Work!! Season 2) – Your Favourite Bio Class Keeps Getting Better!


Author: Hoshi-kun

I’m South African, harbouring an obsession for anything remotely related to Japan, mostly anime, of course. I draw sometimes. Some people call me Naledi, it’s my real name, or something like that. People think I’m stoic because I don’t smile often (I do sometimes). I like languages. Hoshi-kun and Naledi are the same side of the same coin.

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